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DYNC1LI2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM06983G 100 μl / $495

DYNC1LI2 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM06983G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DYNC1LI2 antibody (Center).

Molecular Weight

54099 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human

Immunogen

152-180 aa

Target

This DYNC1LI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human DYNC1LI2.

Isotype

Rabbit Ig

Symbol

DNCLI2, LIC2

GeneID

UniProt ID

Function

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.

Summary

Cytoplasmic dynein is a microtubule-associated motorprotein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM600112) for general information about dyneins.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

Cytoplasmic dynein 1 light intermediate chain 2, Dynein light intermediate chain 2, cytosolic, LIC-2, LIC53/55, DYNC1LI2, DNCLI2, LIC2

Images

DYNC1LI2 Antibody (Center) (Cat. AMM06983G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DYNC1LI2 antibody detected the DYNC1LI2 protein (arrow).

DYNC1LI2 Antibody (Center) (Cat. AMM06983G) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DYNC1LI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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