> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DYNC1LI2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM06983G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DYNC1LI2 antibody (Center).
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Molecular Weight |
54099 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
152-180 aa
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Target |
This DYNC1LI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human DYNC1LI2.
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Isotype |
Rabbit Ig
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Symbol |
DNCLI2, LIC2
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GeneID |
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UniProt ID |
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Function |
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
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Summary |
Cytoplasmic dynein is a microtubule-associated motorprotein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM600112) for general information about dyneins.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
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Synonyms |
Cytoplasmic dynein 1 light intermediate chain 2, Dynein light intermediate chain 2, cytosolic, LIC-2, LIC53/55, DYNC1LI2, DNCLI2, LIC2
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Images |
DYNC1LI2 Antibody (Center) (Cat. AMM06983G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DYNC1LI2 antibody detected the DYNC1LI2 protein (arrow).
DYNC1LI2 Antibody (Center) (Cat. AMM06983G) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DYNC1LI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
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