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FAAH2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM04470G 100 μl / $495

FAAH2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM04470G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FAAH2 antibody (C-term).

Molecular Weight

58304 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

409-438 aa

Target

This FAAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the C-terminal region of human FAAH2.

Isotype

Rabbit Ig

Symbol

AMDD

GeneID

UniProt ID

Function

Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates.

Summary

FAAH2 encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Fatty-acid amide hydrolase 2, Amidase domain-containing protein, Anandamide amidohydrolase 2, Oleamide hydrolase 2, FAAH2, AMDD

Images

Western blot analysis of FAAH2 Antibody (C-term) (Cat. AMM04470G) in HepG2 cell line lysates (35ug/lane).FAAH2 (arrow) was detected using the purified Pab.

FAAH2 Antibody (C-term) (Cat. AMM04470G) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FAAH2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

FAAH2 Antibody (C-term) (Cat. AMM04470G) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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