> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > S47A2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMR09801G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality S47A2 antibody (N-term).
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Molecular Weight |
65085 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
125-153 aa
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Target |
This S47A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the N-terminal region of human S47A2.
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Isotype |
Rabbit Ig
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Symbol |
MATE2
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GeneID |
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UniProt ID |
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Function |
Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.
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Summary |
S47A2 belongs to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Multidrug and toxin extrusion protein 2, MATE-2, hMATE-2, Kidney-specific H(+)/organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2
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Images |
S47A2 Antibody (N-term) (Cat. AMR09801G) western blot analysis in mouse kidney tissue and A2058 cell line lysates (35ug/lane).This demonstrates the S47A2 antibody detected the S47A2 protein (arrow). |
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Specification |
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Quantity |
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