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S47A2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMR09801G 100 μl / $495

S47A2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMR09801G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S47A2 antibody (N-term).

Molecular Weight

65085 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

125-153 aa

Target

This S47A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the N-terminal region of human S47A2.

Isotype

Rabbit Ig

Symbol

MATE2

GeneID

UniProt ID

Function

Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes.

Summary

S47A2 belongs to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Multidrug and toxin extrusion protein 2, MATE-2, hMATE-2, Kidney-specific H(+)/organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2

Images

S47A2 Antibody (N-term) (Cat. AMR09801G) western blot analysis in mouse kidney tissue and A2058 cell line lysates (35ug/lane).This demonstrates the S47A2 antibody detected the S47A2 protein (arrow).

Specification

Quantity

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