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CAPZB Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR15268G 100 μl / $495

CAPZB Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR15268G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CAPZB antibody (N-term).

Molecular Weight

31350 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere

Host

Rabbit

Species Reactivity

Human

Immunogen

54-81 aa

Target

This CAPZB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human CAPZB.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Summary

CAPZB is a member of the F-actin capping protein family. This protein is the beta subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

F-actin-capping protein subunit beta, CapZ beta, CAPZB

Images

Western blot analysis of lysates from Jurkat, HeLa cell line (from left to right), using CAPZB Antibody (N-term)(Cat. APR15268G). APR15268G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Specification

Quantity

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