> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > JTV1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM06046G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality JTV1 antibody (Center).
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Molecular Weight |
35349 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytosol. Nucleus. Note=Following DNA damage, dissociates from the aminoacyl-tRNA synthase complex and translocates from the cytoplasm to the nucleus.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
156-184 aa
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Target |
This JTV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human JTV1.
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Isotype |
Rabbit Ig
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Symbol |
JTV1
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GeneID |
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UniProt ID |
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Function |
Required for assembly and stability of the aminoacyl- tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down- regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
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Summary |
JTV1 is probable core protein of the multisynthetase complex that serves as a template for the assembly of the supramolecular structure. This protein Mediates ubiquitination of FUBP1 and its degradation by the proteasome.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Multisynthase complex auxiliary component p38, Protein JTV-1, AIMP2, JTV1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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