> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > (Mouse) Sox2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM08738G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality (Mouse) Sox2 antibody (N-term).
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Molecular Weight |
34454 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:17097055}
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
This Mouse Sox2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the N-terminal region of mouse Sox2.
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Isotype |
Rabbit Ig
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Symbol |
Sox-2
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GeneID |
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UniProt ID |
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Function |
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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Summary |
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Transcription factor SOX-2, Sox2, Sox-2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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