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B4GALT4 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR15120G 100 μl / $495

B4GALT4 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR15120G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality B4GALT4 antibody (Center).

Molecular Weight

40041 Da

Cellular Localization

Antigen Cellular Localization: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Trans cisternae of Golgi stack

Host

Rabbit

Species Reactivity

Human

Immunogen

91-117 aa

Target

This B4GALT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-117 amino acids from the Central region of human B4GALT4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

Summary

This gene is one of seven beta-1,4-galactosyltransferase(beta4GalT) genes. They encode type II membrane-bound glycoproteinsthat appear to have exclusive specificity for the donor substrateUDP-galactose; all transfer galactose in a beta1,4 linkage tosimilar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has adistinct function in the biosynthesis of different glycoconjugatesand saccharide structures. As type II membrane proteins, they havean N-terminal hydrophobic signal sequence that directs the proteinto the Golgi apparatus and which then remains uncleaved to functionas a transmembrane anchor. By sequence similarity, the beta4GalTsform four groups: beta4GalT1 and beta4GalT2, beta4GalT3 andbeta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzymeencoded by this gene appears to mainly play a role in glycolipidbiosynthesis. Two alternatively spliced transcript variants havebeen found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Beta-1, 4-galactosyltransferase 4, Beta-1, 4-GalTase 4, Beta4Gal-T4, b4Gal-T4, 241-, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 4, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 4, N-acetyllactosamine synthase, Nal synthase, Lactotriaosylceramide beta-1, 4-galactosyltransferase, Beta-N-acetylglucosaminyl-glycolipid beta-1, 4-galactosyltransferase, B4GALT4

Images

B4GALT4 Antibody (Center) (Cat. APR15120G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the B4GALT4 antibody detected the B4GALT4 protein (arrow).

Specification

Quantity

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