> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LETM1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR08210G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LETM1 antibody (C-term).
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Molecular Weight |
83354 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion inner membrane; Single-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
577-607 aa
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Target |
This LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-607 amino acids from the C-terminal region of human LETM1.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.
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Summary |
This gene encodes a protein that is localized to the innermitochondrial membrane. The protein functions to maintain themitochondrial tubular shapes and is required for normalmitochondrial morphology and cellular viability. Mutations in thisgene cause Wolf-Hirschhorn syndrome, a complex malformationsyndrome caused by the deletion of parts of the distal short arm ofchromosome 4. Related pseudogenes have been identified onchromosomes 8, 15 and 19.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
LETM1 and EF-hand domain-containing protein 1, mitochondrial, Leucine zipper-EF-hand-containing transmembrane protein 1, LETM1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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