> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PTDSS1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
AMM07372G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTDSS1 antibody (C-term).
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Molecular Weight |
55528 Da
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Highly enriched in the mitochondria-associated membrane (MAM).
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
390-418 aa
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Target |
This PTDSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human PTDSS1.
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Isotype |
Rabbit Ig
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Symbol |
KIAA0024, PSSA
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GeneID |
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UniProt ID |
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Function |
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
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Summary |
Phosphatidylserine (PS) accounts for 5 to 10% of cellmembrane phospholipids. In addition to its role as a structuralcomponent, PS is involved in cell signaling, blood coagulation, andapoptosis. PS is synthesized by a calcium-dependent base-exchangereaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, thatexchange L-serine for the polar head group of phosphatidylcholine(PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al.,2001 [PubMed 11084049]).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Phosphatidylserine synthase 1, PSS-1, PtdSer synthase 1, Serine-exchange enzyme I, PTDSS1, KIAA0024, PSSA
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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