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NDRG4 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM06584G 100 μl / $495

NDRG4 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM06584G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NDRG4 antibody (Center).

Molecular Weight

38459 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytosol

Host

Rabbit

Species Reactivity

Human

Immunogen

193-220 aa

Target

This NDRG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-220 amino acids from the Central region of human NDRG4.

Isotype

Rabbit Ig

Symbol

BDM1, KIAA1180

GeneID

UniProt ID

Function

Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.

Summary

This gene is a member of the N-myc downregulated genefamily which belongs to the alpha/beta hydrolase superfamily. Theprotein encoded by this gene is a cytoplasmic protein that may beinvolved in the regulation of mitogenic signalling in vascularsmooth muscles cells. Several alternatively spliced transcriptvariants of this gene have been described, but the full-lengthnature of some of these variants has not been determined. [providedby RefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Protein NDRG4, Brain development-related molecule 1, N-myc downstream-regulated gene 4 protein, Vascular smooth muscle cell-associated protein 8, SMAP-8, NDRG4, BDM1, KIAA1180

Images

NDRG4 Antibody (Center) (Cat. AMM06584G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NDRG4 antibody detected the NDRG4 protein (arrow).

Specification

Quantity

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