> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > NCDN Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM06568G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NCDN antibody (N-term).
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Molecular Weight |
78864 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytosol. Cell projection, dendrite. Note=Localizes to somatic regions of neurons
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
114-144 aa
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Target |
This NCDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-144 amino acids from the N-terminal region of human NCDN.
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Isotype |
Rabbit Ig
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Symbol |
KIAA0607
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GeneID |
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UniProt ID |
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Function |
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
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Summary |
This gene encodes a leucine-rich cytoplasmic protein,which is highly similar to a mouse protein that negativelyregulates Ca/calmodulin-dependent protein kinase II phosphorylationand may be essential for spatial learning processes. Severalalternatively spliced transcript variants of this gene have beendescribed.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Neurochondrin, NCDN, KIAA0607
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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