> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ARHGEF11 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR15047G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ARHGEF11 antibody (Center).
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Molecular Weight |
167704 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Membrane. Note=Translocated to the membrane upon stimulation
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
605-632 aa
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Target |
This ARHGEF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11.
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Isotype |
Rabbit Ig
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Symbol |
KIAA0380
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GeneID |
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UniProt ID |
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Function |
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.
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Summary |
Rho GTPases play a fundamental role in numerous cellularprocesses that are initiated by extracellular stimuli that workthrough G protein coupled receptors. The encoded protein may form acomplex with G proteins and stimulate Rho-dependent signals. Asimilar protein in rat interacts with glutamate transporter EAAT4and modulates its glutamate transport activity. Expression of therat protein induces the reorganization of the actin cytoskeletonand its overexpression induces the formation of membrane rufflingand filopodia. Two alternative transcripts encoding differentisoforms have been described.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Rho guanine nucleotide exchange factor 11, PDZ-RhoGEF, ARHGEF11, KIAA0380
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Images |
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Specification |
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Quantity |
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| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
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| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
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| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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