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SHBG Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR09925G 100 μl / $495

SHBG Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR09925G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SHBG antibody (N-term).

Molecular Weight

43779 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Note=In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis

Host

Rabbit

Species Reactivity

Human

Immunogen

69-96 aa

Target

This SHBG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids from the N-terminal region of human SHBG.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.

Summary

This gene encodes a steroid binding protein that was firstdescribed as a plasma protein secreted by the liver but is nowthought to participate in the regulation of steroid responses. Theencoded protein binds each steroid molecule as a dimer formed fromidentical or nearly identical monomers. The use of alternatepromoters and alternatively spliced transcripts have beendescribed. Multiple transcript variants encoding different isoformshave been found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Sex hormone-binding globulin, SHBG, Sex steroid-binding protein, SBP, Testis-specific androgen-binding protein, ABP, Testosterone-estradiol-binding globulin, TeBG, Testosterone-estrogen-binding globulin, SHBG

Images

SHBG Antibody (N-term) (Cat. APR09925G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SHBG antibody detected the SHBG protein (arrow).

Specification

Quantity

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