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APPBP2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM05610G 100 μl / $495

APPBP2 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM05610G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APPBP2 antibody (Center).

Molecular Weight

66853 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Associated with membranes and microtubules

Host

Rabbit

Species Reactivity

Human

Immunogen

243-271 aa

Target

This APPBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human APPBP2.

Isotype

Rabbit Ig

Symbol

KIAA0228, PAT1

GeneID

UniProt ID

Function

May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Summary

The protein encoded by this gene interacts withmicrotubules and is functionally associated with beta-amyloidprecursor protein transport and/or processing. The beta-amyloidprecursor protein is a cell surface protein with signal-transducingproperties, and it is thought to play a role in the pathogenesis ofAlzheimer's disease. This gene has been found to be highlyexpressed in breast cancer. Multiple polyadenylation sites havebeen found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, APP-BP2, Protein interacting with APP tail 1, APPBP2, KIAA0228, PAT1

Images

Anti-APPBP2 Antibody (Center) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 67 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

APPBP2 Antibody (Center) (Cat. AMM05610G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the APPBP2 antibody detected the APPBP2 protein (arrow).

Specification

Quantity

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