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PLA2G12A Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMR09315G 100 μl / $495

PLA2G12A Antibody (Center)

Brand

Leading Biology

Catalog Number

AMR09315G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLA2G12A antibody (Center).

Molecular Weight

21067 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Cytoplasm

Host

Rabbit

Species Reactivity

Human

Immunogen

55-83 aa

Target

This PLA2G12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-83 amino acids from the Central region of human PLA2G12A.

Isotype

Rabbit Ig

Symbol

PLA2G12

GeneID

UniProt ID

Function

PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl- phosphatidylcholine or -phosphatidylethanolamine.

Summary

Secreted phospholipase A2 (sPLA2) enzymes liberatearachidonic acid from phospholipids for production of eicosanoidsand exert a variety of physiologic and pathologic effects. GroupXII sPLA2s, such as PLA2G12A, have relatively low specific activityand are structurally and functionally distinct from other sPLA2s(Gelb et al., 2000 [PubMed 11031251]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Group XIIA secretory phospholipase A2, GXII sPLA2, sPLA2-XII, Phosphatidylcholine 2-acylhydrolase 12A, PLA2G12A, PLA2G12

Images

PLA2G12A Antibody (Center) (Cat. AMR09315G) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PLA2G12A antibody detected the PLA2G12A protein (arrow).

Western blot analysis of PLA2G12A (arrow) using rabbit polyclonal PLA2G12A Antibody (Center) (Cat. AMR09315G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PLA2G12A gene.

Specification

Quantity

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