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TAS1R1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR13688G 100 μl / $495

TAS1R1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR13688G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TAS1R1 antibody (Center).

Molecular Weight

93074 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

323-351 aa

Target

This TAS1R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the Central region of human TAS1R1.

Isotype

Rabbit Ig

Symbol

GPR70, T1R1, TR1

GeneID

UniProt ID

Function

Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.

Summary

The protein encoded by this gene is a G protein-coupledreceptor and is a component of the heterodimeric amino acid tastereceptor T1R1+3. The T1R1+3 receptor responds to L-amino acids butnot to D-enantiomers or other compounds. Most amino acids that areperceived as sweet activate T1R1+3, and this activation is strictlydependent on an intact T1R1+3 heterodimer. Multiple transcriptvariants encoding different isoforms have been found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Taste receptor type 1 member 1, G-protein coupled receptor 70, TAS1R1, GPR70, T1R1, TR1

Images

All lanes : Anti-TAS1R1 Antibody (Center) at 1:1000 dilution Lane 1: A375 whole cell lysate Lane 2: NCI-H1299 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 93 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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