> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > AGFG1 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR14875G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality AGFG1 antibody (N-term).
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Molecular Weight |
58260 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cytoplasmic vesicle.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
1-30 aa
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Target |
This AGFG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AGFG1.
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Isotype |
Rabbit Ig
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Symbol |
HRB, RAB, RIP
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GeneID |
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UniProt ID |
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Function |
Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
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Summary |
The protein encoded by this gene is related tonucleoporins, a class of proteins that mediate nucleocytoplasmictransport. The encoded protein binds the activation domain of thehuman immunodeficiency virus Rev protein when Rev is assembled ontoits RNA target, and is required for the nuclear export ofRev-directed RNAs. Multiple transcript variants encoding differentisoforms have been found for this gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Arf-GAP domain and FG repeat-containing protein 1, HIV-1 Rev-binding protein, Nucleoporin-like protein RIP, Rev-interacting protein, Rev/Rex activation domain-binding protein, AGFG1, HRB, RAB, RIP
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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