> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CD200R1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR11031G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD200R1 antibody (C-term).
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Molecular Weight |
36620 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 2: Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
275-303 aa
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Target |
This CD200R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the C-terminal region of human CD200R1.
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Isotype |
Rabbit Ig
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Symbol |
CD200R, CRTR2, MOX2R, OX2R
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GeneID |
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UniProt ID |
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Function |
Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of proinflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200.
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Summary |
This gene encodes a receptor for the OX-2 membraneglycoprotein. Both the receptor and substrate are cell surfaceglycoproteins containing two immunoglobulin-like domains. Thisreceptor is restricted to the surfaces of myeloid lineage cells andthe receptor-substrate interaction may function as a myeloiddownregulatory signal. Mouse studies of a related gene suggest thatthis interaction may control myeloid function in a tissue-specificmanner. Alternative splicing of this gene results in multipletranscript variants.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Cell surface glycoprotein CD200 receptor 1, CD200 cell surface glycoprotein receptor, Cell surface glycoprotein OX2 receptor 1, CD200R1, CD200R, CRTR2, MOX2R, OX2R
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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