> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TNNI2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM08271G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TNNI2 antibody (N-term).
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Molecular Weight |
21339 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
1-30 aa
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Target |
This TNNI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNNI2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
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Summary |
This gene encodes a fast-twitch skeletal muscle protein, amember of the troponin I gene family, and a component of thetroponin complex including troponin T, troponin C and troponin Isubunits. The troponin complex, along with tropomyosin, isresponsible for the calcium-dependent regulation of striated musclecontraction. Mouse studies show that this component is also presentin vascular smooth muscle and may play a role in regulation ofsmooth muscle function. In addition to muscle tissues, this proteinis found in corneal epithelium, cartilage where it is an inhibitorof angiogenesis to inhibit tumor growth and metastasis, and mammarygland where it functions as a co-activator of estrogenreceptor-related receptor alpha. This protein also suppresses tumorgrowth in human ovarian carcinoma. Mutations in this gene causemyopathy and distal arthrogryposis type 2B. Alternatively splicedtranscript variants have been found for this gene. [provided byRefSeq].
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform, TNNI2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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