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GJB5 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APG03038G 100 μl / $495

GJB5 Antibody (Center)

Brand

Leading Biology

Catalog Number

APG03038G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GJB5 antibody (Center).

Molecular Weight

31088 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, gap junction

Host

Rabbit

Species Reactivity

Human

Immunogen

89-119 aa

Target

This GJB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-119 amino acids from the Central region of human GJB5.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Summary

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) such as GJB5 are thought to play crucial functional roles associated with these channels.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, WB, E

Dilution

IHC-P~~1:50~100 WB~~1:1000

Synonyms

Gap junction beta-5 protein, Connexin-311, Cx311, GJB5

Images

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GJB5 Antibody (Center) (Cat. APG03038G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

GJB5 Antibody (R104.Connexin) (Cat. APG03038G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the GJB5 antibody detected the GJB5 protein (arrow).

Specification

Quantity

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