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KRT7 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR14351G 100 μl / $495

KRT7 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR14351G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KRT7 antibody (N-term).

Molecular Weight

51386 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

111-139 aa

Target

This KRT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human KRT7.

Isotype

Rabbit Ig

Symbol

SCL

GeneID

UniProt ID

Function

Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).

Summary

The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. This type II cytokeratin is specificallyexpressed in the simple epithelia lining the cavities of theinternal organs and in the gland ducts and blood vessels. The genesencoding the type II cytokeratins are clustered in a region ofchromosome 12q12-q13. Alternative splicing may result in severaltranscript variants; however, not all variants have been fullydescribed.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL

Images

KRT7 Antibody (N-term) (Cat. APR14351G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the KRT7 antibody detected the KRT7 protein (arrow).

KRT7 Antibody (N-term) (APR14351G)immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KRT7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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