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MINPP1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR17382G 100 μl / $495

MINPP1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR17382G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MINPP1 antibody (C-term).

Molecular Weight

55051 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}

Host

Rabbit

Species Reactivity

Human

Immunogen

370-398 aa

Target

This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-398 amino acids from the C-terminal region of human MINPP1.

Isotype

Rabbit Ig

Symbol

MIPP

GeneID

UniProt ID

Function

Acts as a phosphoinositide 5- and phosphoinositide 6- phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3- phosphoglycerate. May play a role in bone development (endochondral ossification).

Summary

This gene encodes multiple inositol polyphosphatephosphatase; an enzyme that removes 3-phosphate from inositolphosphate substrates. It is the only enzyme known to hydrolzyeinositol pentakisphosphate and inositol hexakisphosphate. Thisenzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to2-phosphoglycerate; an activity formerly thought to be exclusive to2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Lueberingshunt of the glycolytic pathway.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Multiple inositol polyphosphate phosphatase 1, 3-bisphosphoglycerate 3-phosphatase, 3-BPG phosphatase, Inositol (1, 5)-tetrakisphosphate 3-phosphatase, Ins(1, 5)P(4) 3-phosphatase, MINPP1, MIPP

Images

MINPP1 Antibody (C-term) (Cat. APR17382G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MINPP1 antibody detected the MINPP1 protein (arrow).

MINPP1 Antibody (C-term) (Cat. APR17382G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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