> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MINPP1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR17382G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MINPP1 antibody (C-term).
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Molecular Weight |
55051 Da
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
370-398 aa
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Target |
This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-398 amino acids from the C-terminal region of human MINPP1.
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Isotype |
Rabbit Ig
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Symbol |
MIPP
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GeneID |
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UniProt ID |
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Function |
Acts as a phosphoinositide 5- and phosphoinositide 6- phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3- phosphoglycerate. May play a role in bone development (endochondral ossification).
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Summary |
This gene encodes multiple inositol polyphosphatephosphatase; an enzyme that removes 3-phosphate from inositolphosphate substrates. It is the only enzyme known to hydrolzyeinositol pentakisphosphate and inositol hexakisphosphate. Thisenzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to2-phosphoglycerate; an activity formerly thought to be exclusive to2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Lueberingshunt of the glycolytic pathway.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Multiple inositol polyphosphate phosphatase 1, 3-bisphosphoglycerate 3-phosphatase, 3-BPG phosphatase, Inositol (1, 5)-tetrakisphosphate 3-phosphatase, Ins(1, 5)P(4) 3-phosphatase, MINPP1, MIPP
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Images |
MINPP1 Antibody (C-term) (Cat. APR17382G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MINPP1 antibody detected the MINPP1 protein (arrow).
MINPP1 Antibody (C-term) (Cat. APR17382G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
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| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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