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CPT1A Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APG02749G 100 μl / $495

CPT1A Antibody (C-term)

Brand

Leading Biology

Catalog Number

APG02749G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CPT1A antibody (C-term).

Molecular Weight

88368 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion outer membrane; Multi- pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

728-756 aa

Target

This CPT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 728-756 amino acids from the C-terminal region of human CPT1A.

Isotype

Rabbit Ig

Symbol

CPT1

GeneID

UniProt ID

Function

Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism.

Summary

The mitochondrial oxidation of long-chain fatty acids isinitiated by the sequential action of carnitinepalmitoyltransferase I (which is located in the outer membrane andis detergent-labile) and carnitine palmitoyltransferase II (whichis located in the inner membrane and is detergent-stable), togetherwith a carnitine-acylcarnitine translocase. CPT I is the key enzymein the carnitine-dependent transport across the mitochondrial innermembrane and its deficiency results in a decreased rate of fattyacid beta-oxidation. Alternatively spliced transcript variantsencoding different isoforms have been found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A, CPT1A, CPT1

Images

CPT1A Antibody (C-term) (Cat. APG02749G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CPT1A antibody detected the CPT1A protein (arrow).

Specification

Quantity

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