> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PDE8A Antibody (Center) (L572)Brand |
Leading Biology | Catalog Number |
AMM07062G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PDE8A antibody (Center) (L572).
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Molecular Weight |
93304 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
557-587 aa
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Target |
This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
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Summary |
PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:50
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Synonyms |
High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A, PDE8A
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Images |
Western blot analysis of PDE8A Antibody (Center) (L572) ( AMM07062G) in HL60 cell line lysates (35ug/lane). PDE8A (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PDE8A antibody (Center) (L572)(Cat. AMM07062G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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