> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DSG1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR14319G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DSG1 antibody (Center).
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Molecular Weight |
113748 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
471-499 aa
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Target |
This DSG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-499 amino acids from the Central region of human DSG1.
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Isotype |
Rabbit Ig
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Symbol |
CDHF4
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GeneID |
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UniProt ID |
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Function |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
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Summary |
Desmosomes are cell-cell junctions between epithelial,myocardial and certain other cell types. Desmoglein 1 is acalcium-binding transmembrane glycoprotein component of desmosomesin vertebrate epithelial cells. Currently, three desmogleinsubfamily members have been identified and all are members of thecadherin cell adhesion molecule superfamily. These desmoglein genefamily members are located in a cluster on chromosome 18. Theprotein encoded by this gene has been identified as the autoantigenof the autoimmune skin blistering disease pemphigus foliaceus.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Desmoglein-1, Cadherin family member 4, Desmosomal glycoprotein 1, DG1, DGI, Pemphigus foliaceus antigen, DSG1, CDHF4
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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