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PPEF2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR12935G 100 μl / $495

PPEF2 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR12935G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPEF2 antibody (Center).

Molecular Weight

86518 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment Note=Localized to photoreceptors, PPEF-2(L) is at least 2 fold more abundant in rod inner segments than in the outer segments

Host

Rabbit

Species Reactivity

Human

Immunogen

304-333 aa

Target

This PPEF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human PPEF2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

May play a role in phototransduction. May dephosphorylate photoactivated rhodopsin. May function as a calcium sensing regulator of ionic currents, energy production or synaptic transmission.

Summary

This gene encodes a member of the serine/threonine proteinphosphatase with EF-hand motif family. The protein contains aprotein phosphatase catalytic domain, and at least two EF-handcalcium-binding motifs in its C terminus. Although its substrate(s)is unknown, the encoded protein, which is expressed specifically inphotoreceptors and the pineal, has been suggested to play a role inthe visual system. This gene shares high sequence similarity withthe Drosophila retinal degeneration C (rdgC) gene. [provided byRefSeq].

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Serine/threonine-protein phosphatase with EF-hands 2, PPEF-2, PPEF2

Images

Western blot analysis of lysate from Y79 cell line, using PPEF2 Antibody (Center)(Cat. APR12935G). APR12935G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

PPEF2 Antibody (Center) (APR12935G)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PPEF2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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