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RGS9 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMM07602G 100 μl / $495

RGS9 Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMM07602G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RGS9 antibody (N-term).

Molecular Weight

76966 Da

Cellular Localization

Antigen Cellular Localization: Isoform 3: Membrane; Peripheral membrane protein. Note=Isoform 3 is targeted to the membrane via its interaction with RGS9BP.

Host

Rabbit

Species Reactivity

Human

Immunogen

149-178 aa

Target

This RGS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-178 amino acids from the N-terminal region of human RGS9.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).

Summary

This gene encodes a member of the RGS family of GTPaseactivating proteins that function in various signaling pathways byaccelerating the deactivation of G proteins. This protein isanchored to photoreceptor membranes in retinal cells anddeactivates G proteins in the rod and cone phototransductioncascades. Mutations in this gene result in bradyopsia. Multipletranscript variants encoding different isoforms have been found forthis gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Regulator of G-protein signaling 9, RGS9, RGS9

Images

RGS9 Antibody (N-term) (Cat. AMM07602G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RGS9 antibody detected the RGS9 protein (arrow).

RGS9 Antibody (N-term) (AMM07602G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RGS9 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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