> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CYTH1 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR15656G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CYTH1 antibody (N-term).
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Molecular Weight |
46413 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Peripheral membrane protein Cytoplasm, cytosol
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
37-65 aa
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Target |
This CYTH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human CYTH1.
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Isotype |
Rabbit Ig
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Symbol |
D17S811E, PSCD1
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GeneID |
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UniProt ID |
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Function |
Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.
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Summary |
The protein encoded by this gene is a member of the PSCDfamily. Members of this family have identical structuralorganization that consists of an N-terminal coiled-coil motif, acentral Sec7 domain, and a C-terminal pleckstrin homology (PH)domain. The coiled-coil motif is involved in homodimerization, theSec7 domain contains guanine-nucleotide exchange protein (GEP)activity, and the PH domain interacts with phospholipids and isresponsible for association of PSCDs with membranes. Members ofthis family appear to mediate the regulation of protein sorting andmembrane trafficking. This gene is highly expressed in naturalkiller and peripheral T cells, and regulates the adhesiveness ofintegrins at the plasma membrane of lymphocytes. The encodedprotein is 83% homologous to that of CYTH2.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, SEC7 homolog B2-1, CYTH1, D17S811E, PSCD1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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