> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CHRNA5 Antibody (Center)Brand |
Leading Biology | Catalog Number |
AMM05778G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CHRNA5 antibody (Center).
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Molecular Weight |
53054 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
187-216 aa
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Target |
This CHRNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human CHRNA5.
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Isotype |
Rabbit Ig
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Symbol |
NACHRA5
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GeneID |
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UniProt ID |
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Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
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Summary |
The protein encoded by this gene is a nicotinicacetylcholine receptor subunit and a member of a superfamily ofligand-gated ion channels that mediate fast signal transmission atsynapses. These receptors are thought to be heteropentamerscomposed of separate but similar subunits. Defects in this genehave been linked to susceptibility to lung cancer type 2 (LNCR2).
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Synonyms |
Neuronal acetylcholine receptor subunit alpha-5, CHRNA5, NACHRA5
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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