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DAO Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR07496G 100 μl / $495

DAO Antibody (Center)

Brand

Leading Biology

Catalog Number

APR07496G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DAO antibody (Center).

Molecular Weight

39474 Da

Cellular Localization

Antigen Cellular Localization: Peroxisome.

Host

Rabbit

Species Reactivity

Human

Immunogen

259-287 aa

Target

This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.

Isotype

Rabbit Ig

Symbol

DAMOX

GeneID

UniProt ID

Function

Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.

Summary

This gene encodes the peroxisomal enzyme D-amino acidoxidase. The enzyme is a flavoprotein which uses flavin adeninedinucleotide (FAD) as its prosthetic group. Its substrates includea wide variety of D-amino acids, but it is inactive on thenaturally occurring L-amino acids. Its biological function is notknown; it may act as a detoxifying agent which removes D-aminoacids that accumulate during aging. In mice, it degrades D-serine,a co-agonist of the NMDA receptor. This gene may play a role in thepathophysiology of schizophrenia.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX

Images

DAO Antibody (Center) (Cat. APR07496G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the DAO antibody detected the DAO protein (arrow).

Specification

Quantity

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