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GDI2 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR16119G 100 μl / $495

GDI2 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR16119G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GDI2 antibody (Center).

Molecular Weight

50663 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

135-164 aa

Target

This GDI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human GDI2.

Isotype

Rabbit Ig

Symbol

RABGDIB

GeneID

UniProt ID

Function

Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.

Summary

GDP dissociation inhibitors are proteins that regulate theGDP-GTP exchange reaction of members of the rab family, smallGTP-binding proteins of the ras superfamily, that are involved invesicular trafficking of molecules between cellular organelles.GDIs slow the rate of dissociation of GDP from rab proteins andrelease GDP from membrane-bound rabs. GDI2 is ubiquitouslyexpressed. The GDI2 gene contains many repetitive elementsindicating that it may be prone to inversion/deletionrearrangements. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB

Images

GDI2 Antibody (Center) (Cat. APR16119G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GDI2 antibody detected the GDI2 protein (arrow).

GDI2 Antibody (Center) (APR16119G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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