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CD97 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
AMM05725G 100 μl / $495

CD97 Antibody (C-term)

Brand

Leading Biology

Catalog Number

AMM05725G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD97 antibody (C-term).

Molecular Weight

91869 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

707-736 aa

Target

This CD97 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 707-736 amino acids from the C-terminal region of human CD97.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).

Summary

This gene is a member of the EGF-TM7 family of class IIseven-span transmembrane (7-TM) molecules, likely encoded by a genecluster on the short arm of chromosome 19. The encoded product is aglycoprotein that is present on the surface of most activatedleukocytes and spans the membrane seven times, which is a definingfeature of G protein-coupled receptors. The protein has an extendedextracellular region with several N-terminal epidermal growthfactor (EGF)-like domains, which mediate binding to its cellularligand, decay accelerating factor (DAF, CD55), a regulatory proteinof the complement cascade. The presence of structural featurescharacteristic of extracellular matrix proteins and transmembraneproteins suggests that this protein is a receptor involved in bothcell adhesion and signaling processes early after leukocyteactivation. Alternative splicing has been observed for this geneand three variants have been found.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97

Images

CD97 Antibody (C-term) (Cat. AMM05725G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CD97 antibody detected the CD97 protein (arrow).

CD97 Antibody (C-term) (Cat. AMM05725G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD97 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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