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BEAN Antibody (N-term)

APR11508G Product Datasheet Protocol

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APR11508G		100 μl / $495

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Leading Biology Inc.

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BEAN Antibody (N-term)

Brand	Leading Biology	Catalog Number	APR11508G
Product Type	Polyclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BEAN antibody (N-term).
Molecular Weight	28626 Da
Cellular Localization	Antigen Cellular Localization: Membrane; Single-pass membrane protein
Host	Rabbit
Species Reactivity	Human
Immunogen	45-73 aa
Target	This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human BEAN.
Isotype	Rabbit Ig
GeneID	146227
UniProt ID	Q3B7T3
Summary	The protein encoded by this gene is one of severalproteins that interact with NEDD4, a member of a family ofubiquitin-protein ligases. These proteins have PY motifs in commonthat bind to the WW domains of NEDD4. NEDD4 is developmentallyregulated, and is highly expressed in embryonic tissues. Mutationsin this gene (i.e., intronic insertions of >100 copies ofpentanucleotide repeats including a (TGGAA)n sequence) areassociated with spinocerebellar ataxia type 31. Alternativelyspliced transcript variants encoding different isoforms have beenfound for this gene.
Form	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC-P, E
Dilution	WB~~1:1000 IHC-P~~1:10~50
Synonyms	Protein BEAN1, Brain-expressed protein associating with Nedd4 homolog, BEAN, BEAN1
Images	BEAN Antibody (N-term) (Cat. APR11508G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BEAN antibody detected the BEAN protein (arrow). BEAN Antibody (N-term) (Cat. APR11508G)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BEAN Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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