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APOO Antibody (N-term )

Catalog # Availability Size / Price Inquiry
APG01953G 100 μl / $495

APOO Antibody (N-term )

Brand

Leading Biology

Catalog Number

APG01953G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APOO antibody (N-term ).

Molecular Weight

22285 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass membrane protein. Secreted

Host

Rabbit

Species Reactivity

Human

Immunogen

9-38 aa

Target

This APOO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human APOO.

Isotype

Rabbit Ig

Symbol

FAM121B

GeneID

UniProt ID

Function

Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.

Summary

This gene is a member of the apolipoprotein family.Members of this protein family are involved in the transport andmetabolism of lipids. The encoded protein associates with HDL, LDLand VLDL lipoproteins and is characterized by chondroitin-sulfateglycosylation. This protein may be involved in preventing lipidaccumulation in the myocardium in obese and diabetic patients.Alternative splicing results in multiple transcript variants.Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and16.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Apolipoprotein O, Protein FAM121B, APOO, FAM121B

Images

APOO Antibody (N-term ) (Cat. APG01953G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APOO antibody detected the APOO protein (arrow).

APOO Antibody (N-term) (Cat. APG01953G)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of APOO Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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