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CLN3 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR11598G 100 μl / $495

CLN3 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR11598G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLN3 antibody (Center).

Molecular Weight

47623 Da

Cellular Localization

Antigen Cellular Localization: Lysosome membrane; Multi- pass membrane protein. Late endosome

Host

Rabbit

Species Reactivity

Human

Immunogen

235-263 aa

Target

This CLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human CLN3.

Isotype

Rabbit Ig

Symbol

BTS

GeneID

UniProt ID

Function

Involved in microtubule-dependent, anterograde transport of late endosomes and lysosomes.

Summary

This gene encodes a protein that is involved in lysosomalfunction. Mutations in this, as well as other neuronalceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseasescommonly known as Batten disease or collectively known as neuronalceroid lipofuscinoses (NCLs). Many alternatively spliced transcriptvariants have been found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Synonyms

Battenin, Batten disease protein, Protein CLN3, CLN3, BTS

Images

CLN3 Antibody (Center) (Cat. APR11598G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CLN3 antibody detected the CLN3 protein (arrow).

Specification

Quantity

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