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CSHL1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR15612G 100 μl / $495

CSHL1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR15612G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CSHL1 antibody (C-term).

Molecular Weight

25391 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

156-185 aa

Target

This CSHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human CSHL1.

Isotype

Rabbit Ig

Symbol

CSHP1, CSL

GeneID

UniProt ID

Function

May be a novel gestational hormone required to compensate for absence of other members of the GH/CS cluster during gestation.

Summary

The protein encoded by this gene is a member of thesomatotropin/prolactin family of hormones which play an importantrole in growth control. The gene, along with four other relatedgenes, is located at the growth hormone locus on chromosome 17where they are interspersed in the same transcriptionalorientation; an arrangement which is thought to have evolved by aseries of gene duplications. Although the five genes share aremarkably high degree of sequence identity, they are expressedselectively in different tissues. This particular family member isexpressed in placental villi, although it was originally thought tobe a pseudogene. In fact, alternative splicing suggests that themajority of the transcripts would be unable to express a secretedprotein. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Chorionic somatomammotropin hormone-like 1, Chorionic somatomammotropin-like, Lactogen-like, CSHL1, CSHP1, CSL

Images

Western blot analysis of lysate from human placenta tissue lysate, using CSHL1 Antibody (C-term)(Cat. APR15612G). APR15612G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

CSHL1 Antibody (C-term) (Cat. AP13044a)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CSHL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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