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VPS54 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM08499G 100 μl / $495

VPS54 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM08499G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VPS54 antibody (Center).

Molecular Weight

110589 Da

Cellular Localization

Antigen Cellular Localization: Golgi apparatus, trans-Golgi network

Host

Rabbit

Species Reactivity

Mouse

Immunogen

465-491 aa

Target

This VPS54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-491 amino acids from the Central region of human VPS54.

Isotype

Rabbit Ig

Symbol

HCC8

GeneID

UniProt ID

Function

May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.

Summary

This gene encodes for a protein that in yeast forms partof a trimeric vacuolar-protein-sorting complex that is required forretrograde transport of proteins from prevacuoles to the late Golgicompartment. As in yeast, mammalian Vps54 proteins contain acoiled-coil region and dileucine motifs. Alternative splicingresults in multiple transcript variants encoding different isoforms

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Vacuolar protein sorting-associated protein 54, Hepatocellular carcinoma protein 8, Tumor antigen HOM-HCC-8, Tumor antigen SLP-8p, VPS54, HCC8

Images

VPS54 Antibody (Center) (Cat. AMM08499G) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the VPS54 antibody detected the VPS54 protein (arrow).

VPS54 Antibody (Center) (Cat. AMM08499G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VPS54 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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