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PTGR2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
AMR09619G 100 μl / $495

PTGR2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

AMR09619G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTGR2 antibody (N-term).

Molecular Weight

38499 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

65-94 aa

Target

This PTGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human PTGR2.

Isotype

Rabbit Ig

Symbol

ZADH1

GeneID

UniProt ID

Function

Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest activity towards 15-keto-PGE2. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation (By similarity).

Summary

This gene encodes an enzyme involved in the metabolism ofprostaglandins. The encoded protein catalyzes the NADPH-dependentconversion of 15-keto-prostaglandin E2 to15-keto-13,14-dihydro-prostaglandin E2. This protein may also beinvolved in regulating activation of the peroxisomeproliferator-activated receptor. Alternative splicing results inmultiple transcript variants.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Prostaglandin reductase 2, PRG-2, 15-oxoprostaglandin 13-reductase, Zinc-binding alcohol dehydrogenase domain-containing protein 1, PTGR2, ZADH1

Images

PTGR2 Antibody (N-term) (Cat. AMR09619G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PTGR2 antibody detected the PTGR2 protein (arrow).

PTGR2 Antibody (N-term) (Cat. AMR09619G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTGR2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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