> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SEC62 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMM07750G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEC62 antibody (N-term).
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Molecular Weight |
45862 Da
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
1-30 aa
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Target |
This SEC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEC62.
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Isotype |
Rabbit Ig
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Symbol |
TLOC1
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GeneID |
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UniProt ID |
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Function |
Required for preprotein translocation.
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Summary |
The Sec61 complex is the central component of the proteintranslocation apparatus of the endoplasmic reticulum (ER) membrane.The protein encoded by this gene and SEC63 protein are found to beassociated with ribosome-free SEC61 complex. It is speculated thatSec61-Sec62-Sec63 may perform post-translational proteintranslocation into the ER. The Sec61-Sec62-Sec63 complex might alsoperform the backward transport of ER proteins that are subject tothe ubiquitin-proteasome-dependent degradation pathway. The encodedprotein is an integral membrane protein located in the rough ER.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Translocation protein SEC62, Translocation protein 1, TP-1, hTP-1, SEC62, TLOC1
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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