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SLC8A3 Antibody (C-term)

AMM07880G Product Datasheet Protocol

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AMM07880G		100 μl / $495

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Leading Biology Inc.

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SLC8A3 Antibody (C-term)

Brand	Leading Biology	Catalog Number	AMM07880G
Product Type	Polyclonal Antibodies	Field of Research
Product Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC8A3 antibody (C-term).
Molecular Weight	103010 Da
Cellular Localization	Antigen Cellular Localization: Membrane; Multi-pass membrane protein.
Host	Rabbit
Species Reactivity	Human
Immunogen	585-614 aa
Target	This SLC8A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 585-614 amino acids from the C-terminal region of human SLC8A3.
Isotype	Rabbit Ig
Symbol	NCX3
GeneID	6547
UniProt ID	P57103
Function	Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity).
Summary	This gene encodes a member of the sodium/calcium exchangerintegral membrane protein family. Three mammalian isoforms infamily 8 have been identified. Na+/Ca2+ exchange proteins areinvolved in maintaining Ca2+ homeostasis in a wide variety of celltypes. The protein is regulated by intracellular calcium ions andis found in both the plasma membrane and intracellular organellarmembranes, where exchange of Na+ for Ca2+ occurs in an electrogenicmanner. Alternative splicing has been observed for this gene andmultiple variants have been described.
Form	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage & Stability	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Applications	WB, IHC-P, E
Dilution	WB~~1:1000 IHC-P~~1:10~50
Synonyms	Sodium/calcium exchanger 3, Na(+)/Ca(2+)-exchange protein 3, Solute carrier family 8 member 3, SLC8A3, NCX3
Images	SLC8A3 Antibody (C-term) (Cat. AMM07880G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLC8A3 antibody detected the SLC8A3 protein (arrow). SLC8A3 Antibdy (C-term) (Cat. AMM07880G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC8A3 Antibdy (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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