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PEX14 Antibody (Center)

Catalog # Availability Size / Price Inquiry
AMM07100G 100 μl / $495

PEX14 Antibody (Center)

Brand

Leading Biology

Catalog Number

AMM07100G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PEX14 antibody (Center).

Molecular Weight

41237 Da

Cellular Localization

Antigen Cellular Localization: Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

121-150 aa

Target

This PEX14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PEX14.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin.

Summary

This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Synonyms

Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14, PEX14

Images

PEX14 Antibody (Center) (Cat. AMM07100G) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the PEX14 antibody detected the PEX14 protein (arrow).

PEX14 Antibody (Center) (Cat. AMM07100G) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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