> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CTNND2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR11692G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CTNND2 antibody (C-term).
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Molecular Weight |
132656 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Cell junction, adherens junction. Perikaryon. Note=Colocalizes with CDK5 in the cell body of neuronal cells
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
1131-1159 aa
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Target |
This CTNND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1131-1159 amino acids from the C-terminal region of human CTNND2.
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Isotype |
Rabbit Ig
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Symbol |
NPRAP
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GeneID |
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UniProt ID |
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Function |
Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.
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Summary |
This gene encodes an adhesive junction associated proteinof the armadillo/beta-catenin superfamily and is implicated inbrain and eye development and cancer formation. The protein encodedby this gene promotes the disruption of E-cadherin based adherensjunction to favor cell spreading upon stimulation by hepatocytegrowth factor. This gene is overexpressed in prostateadenocarcinomas and is associated with decreased expression oftumor suppressor E-cadherin in this tissue. This gene resides in aregion of the short arm of chromosome 5 that is deleted in Cri duChat syndrome.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Catenin delta-2, Delta-catenin, GT24, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin, CTNND2, NPRAP
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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