> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SCP2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
AMR09841G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SCP2 antibody (N-term).
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Molecular Weight |
58994 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Mitochondrion. Note=Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues Isoform SCP2: Mitochondrion.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
14-43 aa
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Target |
This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human SCP2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
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Summary |
This gene encodes two proteins: sterol carrier protein X(SCPx) and sterol carrier protein 2 (SCP2), as a result oftranscription initiation from 2 independently regulated promoters.The transcript initiated from the proximal promoter encodes thelonger SCPx protein, and the transcript initiated from the distalpromoter encodes the shorter SCP2 protein, with the 2 proteinssharing a common C-terminus. Evidence suggests that the SCPxprotein is a peroxisome-associated thiolase that is involved in theoxidation of branched chain fatty acids, while the SCP2 protein isthought to be an intracellular lipid transfer protein. This gene ishighly expressed in organs involved in lipid metabolism, and mayplay a role in Zellweger syndrome, in which cells are deficient inperoxisomes and have impaired bile acid synthesis. Alternativesplicing of this gene produces multiple transcript variants, someencoding different isoforms.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Synonyms |
Non-specific lipid-transfer protein, NSL-TP, Propanoyl-CoA C-acyltransferase, SCP-chi, SCPX, Sterol carrier protein 2, SCP-2, Sterol carrier protein X, SCP-X, SCP2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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