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SLC16A3 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR09984G 100 μl / $495

SLC16A3 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR09984G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC16A3 antibody (C-term).

Molecular Weight

49469 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Immunogen

433-462 aa

Target

This SLC16A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 433-462 amino acids from the C-terminal region of human SLC16A3.

Isotype

Rabbit Ig

Symbol

MCT4

GeneID

UniProt ID

Function

Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).

Summary

Lactic acid and pyruvate transport across plasma membranesis catalyzed by members of the proton-linked monocarboxylatetransporter (MCT) family, which has been designated solute carrierfamily-16. Each MCT appears to have slightly different substrateand inhibitor specificities and transport kinetics, which arerelated to the metabolic requirements of the tissues in which it isfound. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2(SLC16A7; MIM 603654), are characterized by 12 predictedtransmembrane domains (Price et al., 1998 [PubMed9425115]).

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Monocarboxylate transporter 4, MCT 4, Solute carrier family 16 member 3, SLC16A3, MCT4

Images

SLC16A3 Antibody (C-term) (Cat. APR09984G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLC16A3 antibody detected the SLC16A3 protein (arrow).

SLC16A3 Antibody (C-term) (Cat. APR09984G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC16A3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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