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ACTN3 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR14798G 100 μl / $495

ACTN3 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR14798G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACTN3 antibody (Center).

Molecular Weight

103241 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

409-437 aa

Target

This ACTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-437 amino acids from the Central region of human ACTN3.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Summary

Alpha-actinin is an actin-binding protein with multipleroles in different cell types. This gene expression is limited toskeletal muscle. It is localized to the Z-disc and analogous densebodies, where it helps to anchor the myofibrillar actin filaments

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Synonyms

Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein, ACTN3

Images

ACTN3 Antibody (Center) (Cat. APR14798G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ACTN3 antibody detected the ACTN3 protein (arrow).

ACTN3 Antibody (Center) (Cat. APR14798G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ACTN3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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