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EDN1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR07643G 100 μl / $495

EDN1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR07643G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EDN1 antibody (Center).

Molecular Weight

24425 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

111-138 aa

Target

This EDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human EDN1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Endothelins are endothelium-derived vasoconstrictor peptides.

Summary

The protein encoded by this gene is proteolyticallyprocessed to release a secreted peptide termed endothelin 1. Thispeptide is a potent vasoconstrictor and is produced by vascularendothelial cells. Endothelin 1 also can affect the central nervoussystem. Two transcript variants encoding different isoforms havebeen found for this gene.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 IF~~1:10~50 FC~~1:10~50

Synonyms

Endothelin-1, Preproendothelin-1, PPET1, Endothelin-1, ET-1, Big endothelin-1, EDN1

Images

EDN1 Antibody (Center) (Cat. APR07643G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the EDN1 antibody detected the EDN1 protein (arrow).

EDN1 Antibody (Center) (Cat. APR07643G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ZMYND17 EDN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of EDN1 Antibody (Center)( APR07643G) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specification

Quantity

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