> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ICAM2 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR16796G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ICAM2 antibody (Center).
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Molecular Weight |
30654 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
191-218 aa
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Target |
This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
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Summary |
The protein encoded by this gene is a member of theintercellular adhesion molecule (ICAM) family. All ICAM proteinsare type I transmembrane glycoproteins, contain 2-9immunoglobulin-like C2-type domains, and bind to the leukocyteadhesion LFA-1 protein. This protein may play a role in lymphocyterecirculation by blocking LFA-1-dependent cell adhesion. Itmediates adhesive interactions important for antigen-specificimmune response, NK-cell mediated clearance, lymphocyterecirculation, and other cellular interactions important for immuneresponse and surveillance. Several transcript variants encoding thesame protein have been found for this gene.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, FC, E
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Dilution |
WB~~1:1000
FC~~1:10~50
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Synonyms |
Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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