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NDUAB Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR08637G 100 μl / $495

NDUAB Antibody (Center)

Brand

Leading Biology

Catalog Number

APR08637G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NDUAB antibody (Center).

Molecular Weight

14852 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side

Host

Rabbit

Species Reactivity

Human

Immunogen

64-92 aa

Target

This NDUAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human NDUAB.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Summary

NDUFA11 encodes a subunit of the membrane-boundmitochondrial complex I. Complex I is composed of numerous subunitsand functions as the NADH-ubiquinol reductase of the mitochondrialelectron transport chain. Mutations in this gene are associatedwith severe mitochondrial complex I deficiency. Alternate splicingresults in multiple transcript variants.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Synonyms

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11, Complex I-B147, CI-B147, NADH-ubiquinone oxidoreductase subunit B147, NDUFA11

Images

NDUAB Antibody (Center) (Cat. APR08637G) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the NDUAB antibody detected the NDUAB protein (arrow).

NDUAB antibody (Center) (Cat. APR08637G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NDUAB antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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