> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CCR8 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR11022G |
Product Type |
Polyclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCR8 antibody (C-term).
|
||
Molecular Weight |
40844 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
|
||
Host |
Rabbit
|
||
Species Reactivity |
Human
|
||
Immunogen |
290-317 aa
|
||
Target |
This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CCR8.
|
||
Isotype |
Rabbit Ig
|
||
Symbol |
CKRL1, CMKBR8, CMKBRL2
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Receptor for the chemokine CCL1/SCYA1/I-309. May regulate monocyte chemotaxis and thymic cell line apoptosis. Alternative coreceptor with CD4 for HIV-1 infection.
|
||
Summary |
CCR8 encodes a member of the beta chemokine receptorfamily, which is predicted to be a seven transmembrane proteinsimilar to G protein-coupled receptors. Chemokines and theirreceptors are important for the migration of various cell typesinto the inflammatory sites. This receptor protein preferentiallyexpresses in the thymus. I-309, thymus activation-regulatedcytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1beta) have been identified as ligands of this receptor. Studies ofthis receptor and its ligands suggested its role in regulation ofmonocyte chemotaxis and thymic cell apoptosis. More specifically,this receptor may contribute to the proper positioning of activatedT cells within the antigenic challenge sites and specialized areasof lymphoid tissues. CCR8 is located at the chemokine receptorgene cluster region.
|
||
Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, FC, E
|
||
Dilution |
WB~~1:1000
FC~~1:10~50
|
||
Synonyms |
C-C chemokine receptor type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC chemokine receptor CHEMR1, CMKBRL2, Chemokine receptor-like 1, CKR-L1, GPR-CY6, GPRCY6, TER1, CDw198, CCR8, CKRL1, CMKBR8, CMKBRL2
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 3 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
