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CLIC6 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APG02660G 100 μl / $495

CLIC6 Antibody (Center)

Brand

Leading Biology

Catalog Number

APG02660G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLIC6 antibody (Center).

Molecular Weight

73012 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell membrane; Single-pass membrane protein Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane (By similarity)

Host

Rabbit

Species Reactivity

Human

Immunogen

539-565 aa

Target

This CLIC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-565 amino acids from the Central region of human CLIC6.

Isotype

Rabbit Ig

Symbol

CLIC1L

GeneID

UniProt ID

Function

May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity).

Summary

CLIC6 is a member of the chloride intracellularchannel family of proteins. The gene is part of a large triplicatedregion found on chromosomes 1, 6, and 21. An alternatively splicedtranscript variant has been described, but its biological validityhas not been determined.

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Synonyms

Chloride intracellular channel protein 6, Parchorin, CLIC6, CLIC1L

Images

CLIC6 Antibody (Center) (Cat. APG02660G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CLIC6 antibody detected the CLIC6 protein (arrow).

CLIC6 antibody (Center) (Cat. APG02660G) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CLIC6 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

CLIC6 Antibody (Center) (Cat. APG02660G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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