> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CLIC6 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APG02660G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CLIC6 antibody (Center).
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Molecular Weight |
73012 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cell membrane; Single-pass membrane protein Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane (By similarity)
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
539-565 aa
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Target |
This CLIC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-565 amino acids from the Central region of human CLIC6.
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Isotype |
Rabbit Ig
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Symbol |
CLIC1L
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GeneID |
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UniProt ID |
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Function |
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity).
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Summary |
CLIC6 is a member of the chloride intracellularchannel family of proteins. The gene is part of a large triplicatedregion found on chromosomes 1, 6, and 21. An alternatively splicedtranscript variant has been described, but its biological validityhas not been determined.
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Form |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Synonyms |
Chloride intracellular channel protein 6, Parchorin, CLIC6, CLIC1L
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Images |
CLIC6 Antibody (Center) (Cat. APG02660G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CLIC6 antibody detected the CLIC6 protein (arrow).
CLIC6 antibody (Center) (Cat. APG02660G) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CLIC6 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
CLIC6 Antibody (Center) (Cat. APG02660G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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